Role of Liver And Kidneys In The COVID-19 Patients In A Tertiary Care Hospital

ABSTRACT

Corona virus pandemic started in 2019, is due to severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2), that belongs to the family of coronaviruses and primarily affects the respiratory system. This disease affected millions of people across the world since 2020. This has wide spectrum clinical infection leading to affect in liver and Kidney. So, this study was conducted to illustrate severity of affect of this virus to liver in kidneys in CO VID-19 patients. Blood samples was collected from COVID-19 patients after their consent and access for Liver and Kidney function test in hospital laboratory. The obtained data was statistically analysed with control subjects. Two sample unpaired t-test was done for comparing data with control values obtained. The study was conducted on 50 non co-morbidity COVID-19 patients arriving at tertiary care hospital, Bareilly. And it is compared with LFT & KFT values of 50 healthy subjects. It was obtained that ALT, AS T & BUN values are significantly (P<=0.05) higher in COVID-19 patients. Though the mean values were not high at critical level.By this study we conclude that patients of COVID-19 without co-morbidity don't have critical severity on liver and kidney damage. ALT, AST and BUN could be independent factors for predicting the severity of CO VID-19. Further studies need to be done on these factors.