[Analysis of anti-SARS-CoV-2 IgG antibody titers after mRNA booster vaccination in patients with nonmalignant hematological disorders].
Rinsho Ketsueki
; 64(2): 133-136, 2023.
Article
in Japanese
| MEDLINE | ID: covidwho-2261857
ABSTRACT
In our facility, anti-SARS-CoV-2 mRNA vaccines were given to 21 patients, including 8 with aplastic anemia (AA), 3 with pure red cell aplasia (PRCA), and 10 with immune thrombocytopenic purpura (ITP), and IgG antibody titers were assessed one month after vaccinations. After receiving both a second vaccine and a booster shot, all patients with AA/PRCA treated with cyclosporine A aside from one, had IgG titers that were lower than the median levels of healthy controls. Even if prednisolone (PSL) doses did not go over 10 mg/day, ITP patients receiving PSL therapy were unable to achieve adequate levels of IgG after booster immunizations.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Purpura, Thrombocytopenic, Idiopathic
/
Red-Cell Aplasia, Pure
/
COVID-19
/
Hematologic Diseases
/
Anemia, Aplastic
Topics:
Vaccines
Limits:
Humans
Language:
Japanese
Journal:
Rinsho Ketsueki
Year:
2023
Document Type:
Article
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