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A case of schizophrenia with relapsed catatonia successfully treated with blonanserin transdermal patch.
Hagikura, Minako; Inada, Toshiya.
  • Hagikura M; Toyota West Hospital, Toyota-shi, Japan.
  • Inada T; Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya-shi, Japan.
Neuropsychopharmacol Rep ; 43(1): 150-153, 2023 03.
Article in English | MEDLINE | ID: covidwho-2261858
ABSTRACT

BACKGROUND:

Catatonia is a syndrome that may present with stupor, immobility, and postural retention, and appears in various primary disorders including schizophrenia, depressive disorders, and neurodevelopmental disorders. CASE PRESENTATION In this report, we describe a 34-year-old female patient with schizophrenia, who had previously been treated with antipsychotic agents to improve psychotic symptoms with delusional symptoms and catatonia. However, she relapsed with catatonic symptoms around 1 year after she voluntarily discontinued the prescribed antipsychotic medications by herself. Her catatonia was successfully improved using the transdermal blonanserin patch, a drug formulation globally first approved in Japan in 2019.

DISCUSSION:

Although benzodiazepines or electroconvulsive therapy have been recommended as the first-line treatment of catatonic manifestation observed in psychiatric patients, this patient responded well to antipsychotic blonanserin. From the differential drug responses, catatonia may be the complex of heterogeneous conditions with different pathophysiologies.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents / Catatonia Type of study: Case report / Diagnostic study Limits: Adult / Female / Humans Language: English Journal: Neuropsychopharmacol Rep Year: 2023 Document Type: Article Affiliation country: Npr2.12314

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents / Catatonia Type of study: Case report / Diagnostic study Limits: Adult / Female / Humans Language: English Journal: Neuropsychopharmacol Rep Year: 2023 Document Type: Article Affiliation country: Npr2.12314