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Invasive pneumococcal surveillance to assess the potential benefits of extended spectrum conjugate vaccines (PCV15/PCV20) in older adults.
Humphreys, Hilary; Corcoran, Mary; Mereckiene, Jolita; Cunney, Robert; Cotter, Suzanne.
  • Humphreys H; Department of Clinical Microbiology, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland.
  • Corcoran M; Department of Clinical Microbiology, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland.
  • Mereckiene J; Irish Meningitis and Sepsis Reference Laboratory, Children's Health Ireland at Temple Street, Dublin, Ireland.
  • Cunney R; Health Services Executive - Health Protection Surveillance Centre, Dublin, Ireland.
  • Cotter S; Department of Clinical Microbiology, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland.
Epidemiol Infect ; 151: e27, 2023 01 26.
Article in English | MEDLINE | ID: covidwho-2263589
ABSTRACT
The introduction of pneumococcal conjugate vaccines (PCV) into the childhood vaccination programme has reduced invasive pneumococcal disease (IPD). Although anticipated from data elsewhere, surveillance in Ireland has confirmed reductions in IPD amongst those ⩾65 years of age due to a decline of PCV serotypes in this age group. Currently, direct protection against IPD in the elderly is focused on immunisation with the 23-valent pneumococcal polysaccharide vaccine (PPV23). However, immunity may not be as effective as with PCV and, furthermore, PPV23 uptake is poor in Ireland. Hence, consideration should be given to providing a PCV to this age group.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumococcal Infections / Streptococcus pneumoniae Type of study: Observational study Topics: Vaccines Limits: Aged / Humans Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2023 Document Type: Article Affiliation country: S0950268823000110

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumococcal Infections / Streptococcus pneumoniae Type of study: Observational study Topics: Vaccines Limits: Aged / Humans Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2023 Document Type: Article Affiliation country: S0950268823000110