Efficacy and safety of vector vaccines for the prevention of new coronavirus infection.

ABSTRACT

The review article discusses vaccines against SARS-CoV 2 based on adenovirus vectors currently used in the world. The concept of creating vector vaccines is described. The data of clinical studies on the efficacy and safety of registered adenovirus-vector vaccines for the prevention of new coronavirus infection are presented. The frequency of serious adverse events after their use is described in detail. In addition, the clinical efficacy of vector vaccines for changing genotypes of the Covid 19 virus has been determined. The review analyzes literature data on the safety and efficacy of vector vaccines against coronavirus infection. The vector vaccines currently used against the new coronavirus infection are quite safe and effective even in relation to the new genotypes of the SARS-CoV 2 virus.Copyright © 2022 Authors. All rights reserved.