Potential role of platelets in COVID-19: Implications for thrombosis.
Res Pract Thromb Haemost
; 4(5): 737-740, 2020 Jul.
Article
in English
| MEDLINE | ID: covidwho-2267109
ABSTRACT
For the past 150 years, platelets have been recognized as the major blood component that mediates hemostasis and thrombosis. In more recent years, however, we have come to appreciate that platelets also perform profound immune functions during infection with various pathogens. We now recognize that platelets can also mediate a response to various RNA viruses such as influenza and that many viral infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can affect platelet count. Thrombocytopenia and increased coagulation have been independently associated with increased mortality. This article provides a perspective on the potential roles of platelets during coronavirus disease 2019.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Language:
English
Journal:
Res Pract Thromb Haemost
Year:
2020
Document Type:
Article
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