SARS-CoV-2 infection: pathogenesis, immune responses, diagnosis
Journal of Pure and Applied Microbiology
; 16(3):1425-1440, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-2270604
ABSTRACT
COVI D-19 has emerged as the most alarming infection of the present time instigated by the virus SARS-CoV-2. In spite of advanced research technologies, the exact pathophysiology and treatment of the condition still need to be explored. However, SARS-CoV-2 has several structural and functional similarities that resemble SARS-CoV and MERS-CoV which may be beneficial in exploring the possible treatment and diagnostic strategies for SARS-CoV-2. This review discusses the pathogen phenotype, genotype, replication, pathophysiology, elicited immune response and emerging variants of SARSCoV- 2 and their similarities with other similar viruses. SARS-CoV-2 infection is detected by a number of diagnostics techniques, their advantages and limitations are also discussed in detail. The review also focuses on nanotechnology-based easy and fast detection of SARS-CoV-2 infection. Various pathways which might play a vital role during SARS-CoV-2 infection have been elaborately discussed since immune response plays a major role during viral infections.
Human Immunology and Allergology [VV055], Prion; Viral; Bacterial and Fungal Pathogens of Humans [VV210], Diagnosis of Human Disease [VV720], coronavirus disease 2019, diagnosis, genotypes, human diseases, immune response, lungs, pathogenesis, phenotypes, physiopathology, respiratory diseases, viral diseases, Severe acute respiratory syndrome coronavirus 2, India, Uttar Pradesh, Commonwealth of Nations, lower-middle income countries, medium Human Development Index countries, South Asia, Asia, Severe acute respiratory syndrome-related coronavirus, Betacoronavirus, Coronavirinae, Coronaviridae, Nidovirales, positive-sense ssRNA Viruses, ssRNA Viruses, RNA Viruses, viruses, SARS-COV-2 variants, immunity reactions, immunological reactions, pathophysiology, lung diseases, SARS-CoV-2, viral infections
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Journal of Pure and Applied Microbiology
Year:
2022
Document Type:
Article
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