Newly diagnosed diabetes in patients with COVID-19: in a tertiary care center in central India

ABSTRACT

Background: Diabetes mellitus (DM) is associated with adverse clinical outcomes and high mortality in patients with corona virus disease 2019 (COVID-19). The relationship between diabetes and COVID-19 is known to be bidirectional. Aim: To analyze the rate of new-onset diabetes in COVID-19 patients and asses the clinical outcomes of new-onset diabetes and hyperglycemia among COVID-19 patients Methods: This cross sectional study was enrolled individuals admitted with COVID-19 and newly diagnosed diabetes mellitus. (DM);based on laboratory diagnoses. Results: Analysis showed that 13.7% (84/610) of COVID-19 patients had newly diagnosed DM. Majority of the newly diagnosed diabetic patient was male (58.3%), most of them (33.3%) were 51-60 year age group. Higher incidence of DM was reported in urban population (54.8%). The significant risk factors of diabetes were found family history of diabetes, (53.6%) and obesity (72.6%). Hypertension was the most common (61.7%) comorbidity associated with the DM. Conclusions: Diabetes diagnosed at COVID-19 presentation is associated with lower glucose but higher inflammatory markers and ICU admission, suggesting stress hyperglycemia as a major physiologic mechanism.