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Comparison of the inactivation capacity of various UV wavelengths on SARS-CoV-2.
Matsuura, Ryosuke; Lo, Chieh-Wen; Ogawa, Takayo; Nakagawa, Masaru; Takei, Masami; Matsumoto, Yasunobu; Wada, Satoshi; Aida, Yoko.
  • Matsuura R; Laboratory of Global Infectious Diseases Control Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
  • Lo CW; Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamichou, Itabashi-ku, Tokyo, 173-8610, Japan.
  • Ogawa T; Laboratory of Global Infectious Diseases Control Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
  • Nakagawa M; Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamichou, Itabashi-ku, Tokyo, 173-8610, Japan.
  • Takei M; Laboratory of Global Animal Resource Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.
  • Matsumoto Y; Photonics Control Technology Team, RIKEN Center for Advanced Photonics, Hirosawa 2-1, Wako, 351-0198, Japan.
  • Wada S; Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamichou, Itabashi-ku, Tokyo, 173-8610, Japan.
  • Aida Y; Division of Hematology and Rheumatology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamichou, Itabashi-ku, Tokyo, 173-8610, Japan.
Biochem Biophys Rep ; 32: 101379, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2271306
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a worldwide pandemic. Ultraviolet (UV) is regarded as a very powerful tool against SARS-CoV-2. However, the inactivating effects of different UV wavelengths on SARS-CoV-2 under the same conditions have hardly been compared. Here, we showed that SARS-CoV-2 cultured in Dulbecco's modified Eagle's medium and 2% fetal bovine serum was efficiently inactivated by irradiation with 222, 254, and 265 wavelengths UV, but not at 308 nm. In addition, it was revealed that UV absorption by DMEM-2% FBS is very efficient at 222 nm. Our results present potentially important information for selecting the optimum UV wavelength according to the application.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Biochem Biophys Rep Year: 2022 Document Type: Article Affiliation country: J.bbrep.2022.101379

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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Biochem Biophys Rep Year: 2022 Document Type: Article Affiliation country: J.bbrep.2022.101379