Viral co-infection with human respiratory syncytial virus in suspected acute and severe respiratory tract infections during COVID-19 pandemic in Yaoundé, Cameroon, 2020-2021.
Influenza Other Respir Viruses
; 17(3): e13131, 2023 03.
Article
in English
| MEDLINE | ID: covidwho-2273022
ABSTRACT
BACKGROUND:
Acute lower respiratory tract infections (ALRIs) are one one of the leading causes of morbidity and mortality among people of all ages worldwide, particularly in low- and middle-income countries (LMICs). The purpose of this study was to determine epidemiological characteristics of respiratory viruses in acute respiratory infection (ARI) patients during the COVID-19 pandemic in Yaoundé, Cameroon.METHODS:
Patients were monitored for respiratory symptoms as part of the surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viral infections. Patients of all ages with respiratory symptoms less than 5 days were considered. Sociodemographic and clinical data as well as nasopharyngeal samples was collected from patients. Nasopharyngeal samples were tested for SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) using real-time reverse-transcription polymerase chain reaction methods. Virus distribution and demographic data were analyzed with R version 2.15.1.RESULTS:
From July 2020 to October 2021, 1120 patients were included. The overall viral detection rate was 32.5%, including 9.5% for RSV, 12.6% for influenza virus and 12.8% for SARS-CoV-2. Co-infections were detected in 6.9% of positive cases. While RSV and influenza virus showed seasonal trends, SARS-CoV-2 was detected throughout the study period.CONCLUSION:
We found that during COVID-19 pandemic, respiratory viruses play an important role in etiology of influenza-like illness in Cameroon, and this observation was true for patients of all ages.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Respiratory Tract Infections
/
Viruses
/
Virus Diseases
/
Respiratory Syncytial Virus, Human
/
Respiratory Syncytial Virus Infections
/
Influenza, Human
/
Coinfection
/
COVID-19
Type of study:
Etiology study
/
Observational study
/
Prognostic study
Limits:
Humans
/
Infant, Newborn
Country/Region as subject:
Africa
Language:
English
Journal:
Influenza Other Respir Viruses
Journal subject:
Virology
Year:
2023
Document Type:
Article
Affiliation country:
Irv.13131
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