Risk of death following COVID-19 vaccination or positive SARS-CoV-2 test in young people in England.
Nat Commun
; 14(1): 1541, 2023 03 27.
Article
in English
| MEDLINE | ID: covidwho-2273491
ABSTRACT
Several studies have reported associations between COVID-19 vaccination and risk of cardiac diseases, especially in young people; the impact on mortality, however, remains unclear. We use national, linked electronic health data in England to assess the impact of COVID-19 vaccination and positive SARS-CoV-2 tests on the risk of cardiac and all-cause mortality in young people (12 to 29 years) using a self-controlled case series design. Here, we show there is no significant increase in cardiac or all-cause mortality in the 12 weeks following COVID-19 vaccination compared to more than 12 weeks after any dose. However, we find an increase in cardiac death in women after a first dose of non mRNA vaccines. A positive SARS-CoV-2 test is associated with increased cardiac and all-cause mortality among people vaccinated or unvaccinated at time of testing.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Cause of Death
/
Vaccination
/
COVID-19 Vaccines
/
COVID-19 Testing
/
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
/
Young adult
Country/Region as subject:
Europa
Language:
English
Journal:
Nat Commun
Journal subject:
Biology
/
Science
Year:
2023
Document Type:
Article
Affiliation country:
S41467-023-36494-0
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