Polysaturated fatty acids and their derivatives regulate respiratory infections.
Neumologia y Cirugia de Torax(Mexico)
; 81(1):41-51, 2022.
Article
in Spanish
| EMBASE | ID: covidwho-2278995
ABSTRACT
The regulation of inflammation is a complex pathophysiological process that depends on the production of oxygenated lipid derivatives essential polyunsaturated fatty acids, like omega-3 and omega-6, among which are the lipoxins resolvins and protectins, called specialized pro-resolving lipid mediators (SPM). Their activity is associated with the control of respiratory infection processes to modulate the production of proinflammatory cytokines, avoiding damage due to inflammation-associated necrosis, reducing microbial loads, and promoting tissue remodeling. Therefore, we review some of the biochemical, physiological and immunological aspects of SPM in the regulation of inflammation in respiratory infections.Copyright © 2022, Instituto Nacional de Enfermedades Respiratorias. All rights reserved.
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Database:
EMBASE
Language:
Spanish
Journal:
Neumologia y Cirugia de Torax(Mexico)
Year:
2022
Document Type:
Article
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