An Insight Overview on COVID-19 mRNA Vaccines: Advantageous, Pharmacology, Mechanism of Action, and Prospective Considerations
International immunopharmacology
; 2023.
Article
in English
| EuropePMC | ID: covidwho-2279198
ABSTRACT
The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has urged scientists to present some novel vaccine platforms during this pandemic to provide a rather prolonged immunity against this respiratory viral infection. In spite of many campaigns formed against the administration of mRNA-based vaccines, those platforms were the most novel types, which helped us meet the global demand by developing protection against COVID-19 and reducing the development of severe forms of this respiratory viral infection. Some societies are worry about the COVID-19 mRNA vaccine administration and the potential risk of genetic integration of inoculated mRNA into the human genome. Although the efficacy and long-term safety of mRNA vaccines have not yet been fully clarified, obviously their application has switched the mortality and morbidity of the COVID-19 pandemic. This study describes the structural features and technologies used in producing of COVID-19 mRNA-based vaccines as the most influential factor in controlling this pandemic and a successful pattern for planning to produce other kind of genetic vaccines against infections or cancers.
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Collection:
Databases of international organizations
Database:
EuropePMC
Type of study:
Observational study
/
Prognostic study
Topics:
Vaccines
Language:
English
Journal:
International immunopharmacology
Year:
2023
Document Type:
Article
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