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Ongoing Efforts to Improve Antimicrobial Utilization in Hospitals among African Countries and Implications for the Future.
Saleem, Zikria; Godman, Brian; Cook, Aislinn; Khan, Muhammad Arslan; Campbell, Stephen M; Seaton, Ronald Andrew; Siachalinga, Linda; Haseeb, Abdul; Amir, Afreenish; Kurdi, Amanj; Mwita, Julius C; Sefah, Israel Abebrese; Opanga, Sylvia A; Fadare, Joseph O; Ogunleye, Olayinka O; Meyer, Johanna C; Massele, Amos; Kibuule, Dan; Kalungia, Aubrey C; Shahwan, Moyad; Nabayiga, Hellen; Pichierri, Giuseppe; Moore, Catrin E.
  • Saleem Z; Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan 60800, Pakistan.
  • Godman B; Department of Pharmacoepidemiology, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK.
  • Cook A; Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman 346, United Arab Emirates.
  • Khan MA; Department of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Molotlegi Street, Garankuwa, Pretoria 0208, South Africa.
  • Campbell SM; Centre for Neonatal and Paediatric Infection, St. George's University of London, London SW17 0RE, UK.
  • Seaton RA; Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford OX1 2JD, UK.
  • Siachalinga L; The Indus Hospital, Bedian Road, Lahore 54000, Pakistan.
  • Haseeb A; Department of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Molotlegi Street, Garankuwa, Pretoria 0208, South Africa.
  • Amir A; Centre for Epidemiology and Public Health, School of Health Sciences, University of Manchester, Manchester M13 9PL, UK.
  • Kurdi A; NIHR Greater Manchester Patient Safety Translational Research Centre, School of Health Sciences, University of Manchester, Manchester M13 9PL, UK.
  • Mwita JC; Queen Elizabeth University Hospital, Govan Road, Glasgow G51 4TF, UK.
  • Sefah IA; Scottish Antimicrobial Prescribing Group, Healthcare Improvement Scotland, Delta House, 50 West Nile Street, Glasgow G1 2NP, UK.
  • Opanga SA; College of Pharmacy, Yeungnam University, Daehak-Ro, Gyeongsan, Gyeongbuk 38541, Republic of Korea.
  • Fadare JO; Department of Clinical Pharmacy, College of Pharmacy, Umm Al-Qura University, Makkah 24382, Saudi Arabia.
  • Ogunleye OO; Department of Microbiology, Armed Forces Institute of Pathology, National University of Medical Sciences, Rawalpindi 46000, Pakistan.
  • Meyer JC; Department of Pharmacoepidemiology, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK.
  • Massele A; Department of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Molotlegi Street, Garankuwa, Pretoria 0208, South Africa.
  • Kibuule D; Department of Pharmacology, College of Pharmacy, Hawler Medical University, Erbil 44001, Iraq.
  • Kalungia AC; Center of Research and Strategic Studies, Lebanese French University, Erbil 44001, Iraq.
  • Shahwan M; Department of Internal Medicine, Faculty of Medicine, University of Botswana, Private Bag 0713 UB, Gaborone 00704, Botswana.
  • Nabayiga H; Pharmacy Practice Department, School of Pharmacy, University of Health and Allied Sciences, Volta Region, Hohoe PMB 31, Ghana.
  • Pichierri G; Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, University of Nairobi, Nairobi P.O. Box 19676-00202, Kenya.
  • Moore CE; Department of Pharmacology and Therapeutics, Ekiti State University, Ado Ekiti 362103, Nigeria.
Antibiotics (Basel) ; 11(12)2022 Dec 15.
Article in English | MEDLINE | ID: covidwho-2279430
ABSTRACT
There are serious concerns with rising antimicrobial resistance (AMR) across countries increasing morbidity, mortality and costs. These concerns have resulted in a plethora of initiatives globally and nationally including national action plans (NAPs) to reduce AMR. Africa is no exception, especially with the highest rates of AMR globally. Key activities in NAPs include gaining a greater understanding of current antimicrobial utilization patterns through point prevalence surveys (PPS) and subsequently instigating antimicrobial stewardship programs (ASPs). Consequently, there is a need to comprehensively document current utilization patterns among hospitals across Africa coupled with ASP studies. In total, 33 PPS studies ranging from single up to 18 hospitals were documented from a narrative review with typically over 50% of in-patients prescribed antimicrobials, up to 97.6% in Nigeria. The penicillins, ceftriaxone and metronidazole, were the most prescribed antibiotics. Appreciable extended prescribing of antibiotics up to 6 days or more post-operatively was seen across Africa to prevent surgical site infections. At least 19 ASPs have been instigated across Africa in recent years to improve future prescribing utilizing a range of prescribing indicators. The various findings resulted in a range of suggested activities that key stakeholders, including governments and healthcare professionals, should undertake in the short, medium and long term to improve future antimicrobial prescribing and reduce AMR across Africa.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Reviews Language: English Year: 2022 Document Type: Article Affiliation country: Antibiotics11121824

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Reviews Language: English Year: 2022 Document Type: Article Affiliation country: Antibiotics11121824