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Coronavirus Disease 2019 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of Severe Acute Respiratory Syndrome Coronavirus-2 Pretransplant.
Shah, Sadia Z; Alvarez, Francisco G; Sanghavi, Devang K; Moreno Franco, Pablo; Isha, Shahin; Marquez, Christopher P; Libertin, Claudia; Guru, Pramod K; Sareyyupoglu, Basar; Pham, Si M.
  • Shah SZ; Department of Transplantation, Mayo Clinic, Jacksonville, FL.
  • Alvarez FG; Department of Transplantation, Mayo Clinic, Jacksonville, FL.
  • Sanghavi DK; Department of Critical Care, Mayo Clinic, Jacksonville, FL.
  • Moreno Franco P; Department of Critical Care, Mayo Clinic, Jacksonville, FL.
  • Isha S; Department of Critical Care, Mayo Clinic, Jacksonville, FL.
  • Marquez CP; Department of Lab Medicine and Pathology, Mayo Clinic, Jacksonville, FL.
  • Libertin C; Division of Infectious Disease, Department of Medicine, and Mayo Clinic, Jacksonville, FL.
  • Guru PK; Department of Critical Care, Mayo Clinic, Jacksonville, FL.
  • Sareyyupoglu B; Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL.
  • Pham SM; Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL.
Mayo Clin Proc Innov Qual Outcomes ; 7(2): 93-98, 2023 Apr.
Article in English | MEDLINE | ID: covidwho-2280745
ABSTRACT
Coronavirus disease 2019 (COVID-19) pandemic has led to considerable morbidity and mortality across the world. Lung transplant is a viable option for a few with COVID-19-related lung disease. Whom and when to transplant has been the major question impacting the transplant community given the novelty of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We describe a pitfall of presumed prolonged shedding of SARS-CoV-2 in a patient with COVID-19 associated acute respiratory distress syndrome leading to COVID-19 pneumonia after lung transplant. This raises concerns that replication-competent SARS-CoV-2 virus can persist for months post-infection and can lead to re-infection of grafts in the future.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: Mayo Clin Proc Innov Qual Outcomes Year: 2023 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report Language: English Journal: Mayo Clin Proc Innov Qual Outcomes Year: 2023 Document Type: Article