Risk factors of mucormycosis in post-COVID-19 patients- a retrospective study
Asian Journal of Medical Sciences
; 13(9):17-21, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-2280761
ABSTRACT
Background:
Rhino-orbito-cerebral mucormycosis was seen in increasing severity in the recent second wave of COVID-19 in India. The incidence of mucormycosis is increased significantly in patients with diabetes. The most common cause attributed to the rise of mucormycosis in COVID-19 patients are uncontrolled diabetes. Lymphopenia and increased levels of certain cytokines, such as IL-6, have been closely associated with the disease severity. Aims andObjectives:
The aims of this study were to analyze risk factors involved in Mucormycosis in 2nd wave of COVID-19. Materials andMethods:
The study was done in the Mucormycosis ward, Department of ENT, Patna Medical College and Hospital, Patna, between May 2021 and July 2021. A total of 100 patients of both gender and all age groups were taken into the study.Results:
Out of 100 patients included in the study, 57% (n=57) of patients had history of steroid intake, while 43% (n=43) had no history. About 41% (n=41) of patients needed oxygen support during treatment, while 59% (n=59) had no history of oxygen inhalation. About 88% (n=88) of patients had prior history of diabetes or detected during treatment, while 12% (n=12) had no prior history of diabetes or detected during treatment. About 91% (n=91)of patients had uncontrolled hyperglycemia, while 9% (n=9) had controlled blood sugar level.Conclusion:
Uncontrolled hyperglycemia and delta strain are mainly associated major risk factors that lead to such high number of mucormycosis cases in India (post 2nd wave of COVID-19). Steroid role is not that much significant in our study and oxygen inhalation is not associated with mucormycosis.
Prion; Viral; Bacterial and Fungal Pathogens of Humans [VV210], Non-communicable Human Diseases and Injuries [VV600], Human Immunology and Allergology [VV055], Nutrition related Disorders and Therapeutic Nutrition [VV130], human diseases, mucormycosis, risk factors, coronavirus disease 2019, blood sugar, diabetes mellitus, glucose, insulin, interleukin 6, hyperglycaemia, leukopenia, mycoses, infections, man, Severe acute respiratory syndrome coronavirus 2, Mucorales, India, Kerala, Commonwealth of Nations, lower-middle income countries, medium Human Development Index countries, South Asia, Asia, Homo, Hominidae, primates, mammals, vertebrates, Chordata, animals, eukaryotes, Severe acute respiratory syndrome-related coronavirus, Betacoronavirus, Coronavirinae, Coronaviridae, Nidovirales, positive-sense ssRNA Viruses, ssRNA Viruses, RNA Viruses, viruses, Mucoromycotina, Zygomycota, fungi, SARS-CoV-2, blood glucose, glucose in blood, dextrose, hyperglycemia, high blood glucose, panleukopenia
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Language:
English
Journal:
Asian Journal of Medical Sciences
Year:
2022
Document Type:
Article
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