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A Systematic Review of Economic Evaluations Conducted for Interventions to Screen, Treat, and Manage Retinopathy of Prematurity (ROP) in the United States, United Kingdom, and Canada.
Smith, Andrew F; Sadeq, Aaqib; Kinzel, Eden; Bhambhwani, Vishaal.
  • Smith AF; Department of Ophthalmology, King's College London, London, UK.
  • Sadeq A; Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.
  • Kinzel E; MedMetrics Inc, Wolfville, Nova Scotia, Canada.
  • Bhambhwani V; MedMetrics Inc, Wolfville, Nova Scotia, Canada.
Ophthalmic Epidemiol ; : 1-8, 2022 Jun 14.
Article in English | MEDLINE | ID: covidwho-2281902
ABSTRACT

PURPOSE:

A systematic literature review (SLR) of economic evaluations (EE) conducted for interventions to screen, treat, and manage retinopathy of prematurity (ROP) in the United States (US), United Kingdom (UK), and Canada was performed.

METHODS:

The SLR accessed the MEDLINE, Embase, Cochrane, Web of Science, Health Business Elite, Econ. Lit, NHS EED, and Google Scholar databases over the period 1st January 2000 to 4th August 2021. The key Medical Subject Heading (MeSH) search terms used included Retinopathy of prematurity, Cost-effectiveness analysis, Cost-utility analysis, Cost of illness, Cost-benefit analysis, Cost minimization analysis, Incremental cost-effectiveness ratio, Quality adjusted life years, return on investment, burden of illness, disability adjusted life years, and Economic evaluation. Screening was conducted using Covidence, and the risk of bias was assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist. Data extraction was performed using MS Excel.

RESULTS:

1,527 articles were examined with nine (9) papers identified, one (1) from the UK; two (2) from Canada and six (6) from the US. Cost-effectiveness analysis was the main form of EE conducted (n = 5) and telemedicine screening (n = 3) was found to be highly cost-effective for ROP with the ICER values ranging from £446 to £4,240 per Quality Adjusted Life Year (QALY) in 2021 figures. 73% of included studies complied with the CHEERS checklist for EE.

CONCLUSIONS:

ROP screening and treatment strategies reviewed were highly cost-effective. This review may assist eye health policymakers in planning nationwide screening and treatment programs to combat vision loss and blindness due to ROP.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Reviews / Systematic review/Meta Analysis Language: English Journal: Ophthalmic Epidemiol Journal subject: Epidemiology / Ophthalmology Year: 2022 Document Type: Article Affiliation country: 09286586.2022.2084757

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Reviews / Systematic review/Meta Analysis Language: English Journal: Ophthalmic Epidemiol Journal subject: Epidemiology / Ophthalmology Year: 2022 Document Type: Article Affiliation country: 09286586.2022.2084757