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The physiopathology of COVID acute respiratory failure
Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients ; : 117-128, 2020.
Article in English | Scopus | ID: covidwho-2282058
ABSTRACT
The current COVID-19 pandemic has posed an unusual challenge to health services in all countries. Although physiopathological knowledge about other coronaviruses, mainly SARS-CoV-1 and MERS, has been useful, SARS-CoV-2 has very particular aspects. Its lethality is lower than the previous ones, but its infectivity is much higher, which has resulted in a global expansion, not reached by previous viruses. The physiopathology of acute respiratory failure, in COVID-19, is especially complex and must be understood under a triple prism specific viral action, the immunopathological response (which in turn has several phases) and the microvascular response. The fact that the elderly are particularly fragile to this virus is a particular challenge. Firstly, to understand what the differential physiopathological facts are. Secondly, to transfer this knowledge to the diagnostic and therapeutic field, in an attempt to reduce morbidity and mortality in this age group. At present, we need to continue to deepen our knowledge of the physiopathology of respiratory failure in the elderly in order to achieve the final objective in therapeutic terms. © Springer Nature Switzerland AG 2020.
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Full text: Available Collection: Databases of international organizations Database: Scopus Language: English Journal: Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients Year: 2020 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: Scopus Language: English Journal: Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients Year: 2020 Document Type: Article