Forced oscillation technique used for monitoring of covid19 pneumonia

ABSTRACT

Background: Forcrd oscillation technique (FOT) is a non-invasive method for investigation of lung mechanics without active participation of the patient. The objectives of the study were to find out whether FOT method could be used for monitoring of covid-19 pneumonia (CVP) course and how FOT indices correlate with other, commonly used indicators of disease severity. Method(s) During the hospital stay and 3 months after the discharge from hospital repeated measurements of lung mechanics were performed with portable device Tremoflo-100 (Thorasys, Canada). Result(s) Most relevant differences between disease stages reflected the lung reactance indices - Fres and AX. Indices characterizing the airflow resistance didn't reach the significance level. Correlation analysis also was performed between FOT indices and CT score, body mass index (BMI), patients age, blood CRP and ferritin levels, duration of hospital stay and patients oxygen demand (FiO2). Significant correlations View inline were found only between the last two. The highest significance showed Fres % pred and AX % pred. Fres correlated to FiO2 with R=0,498 and p-0,0000004, but AX% with r=0,502 Conclusion(s) The study has shown that FOT method reflects the changes in lung mechanics occurring during acute phase and recovery period from covid-19 pneumonia. FOT indices correlate with patients oxygen demand and hospital stay-time.