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[Thrombosis with Thrombocytopenia Syndrome after ChAdOx1 nCoV-19 vaccination].
Takatsuki, Mari; Araki, Toshihiko; Kanno, Akira; Yasumoto, Atsushi; Morishita, Eriko; Shiota, Hiroshi.
  • Takatsuki M; Department of Neurology, Kawaguchi Municipal Medical Center.
  • Araki T; Department of Neurology, Kawaguchi Municipal Medical Center.
  • Kanno A; Department of Neurology, Kawaguchi Municipal Medical Center.
  • Yasumoto A; Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital.
  • Morishita E; Department of Laboratory Sciences, Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University.
  • Shiota H; Department of Neurology, Kawaguchi Municipal Medical Center.
Rinsho Shinkeigaku ; 62(6): 487-491, 2022 Jun 24.
Article in Japanese | MEDLINE | ID: covidwho-2283342
ABSTRACT
A 48-year-old Japanese man who had no previous medical history received his first dose of the ChAdOx1 nCoV-19 vaccine. Ten days after the vaccine administration, he developed a headache. Laboratory results indicated throm-bocytopenia and DIC. A head CT revealed microbleeding in the left parietal lobe. Contrast-enhanced CT showed thrombus in the left transverse sinus and left sigmoid sinus. A brain MRI demonstrated venous hemorrhagic infarction and subarachnoid hemorrhages in the left parietal lobe, and whole-body enhanced CT also revealed portal vein embolism and renal infarction. He was diagnosed with thrombosis with thrombocytopenia syndrome, and was treated according to the guideline. He has been recovering with the treatments. This is the first reported case of TTS associated with the ChAdOx1 nCoV-19 vaccine in Japan.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombocytopenia / Thrombosis Type of study: Case report / Prognostic study Topics: Vaccines Limits: Humans / Male / Middle aged Language: Japanese Journal: Rinsho Shinkeigaku Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombocytopenia / Thrombosis Type of study: Case report / Prognostic study Topics: Vaccines Limits: Humans / Male / Middle aged Language: Japanese Journal: Rinsho Shinkeigaku Year: 2022 Document Type: Article