[Thrombosis with Thrombocytopenia Syndrome after ChAdOx1 nCoV-19 vaccination].
Rinsho Shinkeigaku
; 62(6): 487-491, 2022 Jun 24.
Article
in Japanese
| MEDLINE | ID: covidwho-2283342
ABSTRACT
A 48-year-old Japanese man who had no previous medical history received his first dose of the ChAdOx1 nCoV-19 vaccine. Ten days after the vaccine administration, he developed a headache. Laboratory results indicated throm-bocytopenia and DIC. A head CT revealed microbleeding in the left parietal lobe. Contrast-enhanced CT showed thrombus in the left transverse sinus and left sigmoid sinus. A brain MRI demonstrated venous hemorrhagic infarction and subarachnoid hemorrhages in the left parietal lobe, and whole-body enhanced CT also revealed portal vein embolism and renal infarction. He was diagnosed with thrombosis with thrombocytopenia syndrome, and was treated according to the guideline. He has been recovering with the treatments. This is the first reported case of TTS associated with the ChAdOx1 nCoV-19 vaccine in Japan.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Thrombocytopenia
/
Thrombosis
Type of study:
Case report
/
Prognostic study
Topics:
Vaccines
Limits:
Humans
/
Male
/
Middle aged
Language:
Japanese
Journal:
Rinsho Shinkeigaku
Year:
2022
Document Type:
Article
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