SERS-based immunomagnetic bead for rapid detection of H5N1 influenza virus.
Influenza Other Respir Viruses
; 17(3): e13114, 2023 03.
Article
in English
| MEDLINE | ID: covidwho-2286196
ABSTRACT
The surface-enhanced Raman scattering (SERS) has recently drawn attention in the detection of respiratory viruses, but there have been few reports of the direct detection of viruses. In this study, a sandwich immunomagnetic bead SERS was established for the rapid diagnosis of the H5N1 influenza virus. The detection limit was estimated to be 5.0 × 10-6 TCID50/ml. The method showed excellent specificity with no cross-reaction with H1N1, H5N6 or H9N2. The H5N1 influenza virus detection accuracy of the SERS method was 100% in chicken embryos. The results hold great promise for the utilization of SERS as an innovative approach in the diagnosis of influenza virus.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Influenza, Human
/
Influenza A Virus, H1N1 Subtype
/
Influenza A Virus, H5N1 Subtype
/
Influenza A Virus, H9N2 Subtype
/
Influenza in Birds
Type of study:
Diagnostic study
/
Randomized controlled trials
Limits:
Animals
/
Humans
Language:
English
Journal:
Influenza Other Respir Viruses
Journal subject:
Virology
Year:
2023
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS