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Treatment Effects of Integrated TCM and Western Medicine Treatment Scheme on COVID-19: A Single-armed Clinical Trial
Xie, Z.; Liu, S.; Huang, L.; Sun, J.; Tang, Y.; Chen, H.; Qi, J.; Guo, J.; Miao, L.; Yang, H.; Zhang, Y.; Li, Z.; Xu, Y.; Lin, S.; Xun, Y.; Zhang, L.; Bao, J.; Cai, Z.; Huang, J.; Wen, C..
Clinical Complementary Medicine and Pharmacology ; 1(1) (no pagination), 2021.
Article in English | EMBASE | ID: covidwho-2287214
ABSTRACT
Backgroud The outbreak of COVID-19 has brought unprecedented perils to human health and raised public health concerns in more than two hundred countries. Safe and effective treatment scheme is needed urgently. Objective(s) To evaluate the effects of integratedTCM and western medicine treatment scheme on COVID-19. Method(s) A single-armed clinical trial was carried out in Hangzhou Xixi Hospital, an affiliated hospital with Zhejiang Chinese Medical University. 102 confirmed cases were screened out from 725 suspected cases and 93 of them were treated with integrated TCM and western medicine treatment scheme. Result(s) 83 cases were cured, 5 cases deteriorated, and 5 cases withdrew from the study. No deaths were reported. The mean relief time of fever, cough, diarrhea, and fatigue were (4.78 +/- 4.61) days, (7.22 +/- 4.99) days, (5.28 +/- 3.39) days, and (5.28 +/- 3.39) days, respectively. It took (14.84 +/- 5.50) days for SARS-CoV-2 by nucleic acid amplification-based testing to turn negative. Multivariable cox regression analysis revealed that age, BMI, PISCT, BPC, AST, CK, BS, and UPRO were independent risk factors for COVID-19 treatment. Conclusion(s) Our study suggested that integrated TCM and western medicine treatment scheme was effective for COVID-19.Copyright © 2021
Keywords
Chinese medicine, Clinical trial, covid-19, Novel coronavirus pneumonia, adult, age, article, aspartate aminotransferase level, body mass, coronavirus disease 2019/di [Diagnosis], coronavirus disease 2019/dt [Drug Therapy], coughing, diarrhea, drug efficacy, fatigue, female, fever, human, major clinical study, male, middle aged, multivariate analysis, nucleic acid amplification techniques, priority journal, proportional hazards model, risk factor, western medicine, alpha interferon/ct [Clinical Trial], alpha interferon/dt [Drug Therapy], antivirus agent/ct [Clinical Trial], antivirus agent/dt [Drug Therapy], Chinese drug/ct [Clinical Trial], Chinese drug/dt [Drug Therapy], Dioscorea extract/ct [Clinical Trial], Dioscorea extract/dt [Drug Therapy], Forsythia fruit/ct [Clinical Trial], Forsythia fruit/dt [Drug Therapy], lopinavir/ct [Clinical Trial], lopinavir/dt [Drug Therapy], unclassified drug, bai dou kou/ct [Clinical Trial], bai dou kou/dt [Drug Therapy], bi xie/ct [Clinical Trial], bi xie/dt [Drug Therapy], can sha/ct [Clinical Trial], can sha/dt [Drug Therapy], cang zhu/ct [Clinical Trial], cang zhu/dt [Drug Therapy], chan tui/ct [Clinical Trial], chan tui/dt [Drug Therapy], fu ling/ct [Clinical Trial], fu ling/dt [Drug Therapy], guang huo xiang/ct [Clinical Trial], guang huo xiang/dt [Drug Therapy], hou pu/ct [Clinical Trial], hou pu/dt [Drug Therapy], hua shi/ct [Clinical Trial], hua shi/dt [Drug Therapy], Huang Qin/ct [Clinical Trial], Huang Qin/dt [Drug Therapy], jiang ban xia/ct [Clinical Trial], jiang ban xia/dt [Drug Therapy], jin yin hua/ct [Clinical Trial], jin yin hua/dt [Drug Therapy], ku xing ren/ct [Clinical Trial], ku xing ren/dt [Drug Therapy], ma huang/ct [Clinical Trial], ma huang/dt [Drug Therapy], qing hao/ct [Clinical Trial], qing hao/dt [Drug Therapy], shen qu/ct [Clinical Trial], shen qu/dt [Drug Therapy], shi chang pu/ct [Clinical Trial], shi chang pu/dt [Drug Therapy], shi gao/ct [Clinical Trial], shi gao/dt [Drug Therapy], su ye/ct [Clinical Trial], su ye/dt [Drug Therapy], ting li zi/ct [Clinical Trial], ting li zi/dt [Drug Therapy], yi ren/ct [Clinical Trial], yi ren/dt [Drug Therapy], yin chen/ct [Clinical Trial], yin chen/dt [Drug Therapy], zhi gan cao/ct [Clinical Trial], zhi gan cao/dt [Drug Therapy]
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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Clinical Complementary Medicine and Pharmacology Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Clinical Complementary Medicine and Pharmacology Year: 2021 Document Type: Article