Associations of Physical Inactivity and COVID-19 Outcomes Among Subgroups.
Am J Prev Med
; 64(4): 492-502, 2023 04.
Article
in English
| MEDLINE | ID: covidwho-2287982
ABSTRACT
INTRODUCTION:
Physical activity before COVID-19 infection is associated with less severe outcomes. The study determined whether a doseâresponse association was observed and whether the associations were consistent across demographic subgroups and chronic conditions.METHODS:
A retrospective cohort study of Kaiser Permanente Southern California adult patients who had a positive COVID-19 diagnosis between January 1, 2020 and May 31, 2021 was created. The exposure was the median of at least 3 physical activity self-reports before diagnosis. Patients were categorized as follows always inactive, all assessments at 10 minutes/week or less; mostly inactive, median of 0-60 minutes per week; some activity, median of 60-150 minutes per week; consistently active, median>150 minutes per week; and always active, all assessments>150 minutes per week. Outcomes were hospitalization, deterioration event, or death 90 days after a COVID-19 diagnosis. Data were analyzed in 2022.RESULTS:
Of 194,191 adults with COVID-19 infection, 6.3% were hospitalized, 3.1% experienced a deterioration event, and 2.8% died within 90 days. Doseâresponse effects were strong; for example, patients in the some activity category had higher odds of hospitalization (OR=1.43; 95% CI=1.26, 1.63), deterioration (OR=1.83; 95% CI=1.49, 2.25), and death (OR=1.92; 95% CI=1.48, 2.49) than those in the always active category. Results were generally consistent across sex, race and ethnicity, age, and BMI categories and for patients with cardiovascular disease or hypertension.CONCLUSIONS:
There were protective associations of physical activity for adverse COVID-19 outcomes across demographic and clinical characteristics. Public health leaders should add physical activity to pandemic control strategies.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Exercise
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
North America
Language:
English
Journal:
Am J Prev Med
Journal subject:
Public Health
Year:
2023
Document Type:
Article
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