Analysis laboratory results of three cases of COVID-19 complicated with falciparum malaria
China Tropical Medicine
; 23(1):106-108, 2023.
Article
in Chinese
| CAB Abstracts | ID: covidwho-2288789
ABSTRACT
Objective:
To analyze the laboratory indexes of patients infected with malaria patients and COVID-19, so as to provide reliable evidence for the diagnosis of mixed infection of both. Methods The routine clinical laboratory items such as routine blood, biochemistry and lymphocyte subsets were tested in three cases of COVID-19 complicated with falciparum malaria who admitted to Guangzhou Eighth People's Hospital Affiliated to Guangzhou Medical University from July to December 2020 were tested. Laboratory data were stage-wise analyzed in conjunction with changes in the course of disease. Results Three patients confirmed COVID-19 infection recruited all had malaria infection history. Fever, headache, and other symptoms emerged on the 4rd to 11th day after admission. Malaria parasite was detected by malaria parasite antigen testing and blood smear testing, and all three patients had re-ignition of malaria after being confirmed COVID-19 infection. In the early stage of malaria relapse, lymphocytes decreased, CRP and SAA increased, and gradually returned to normal level after antimalarial treatment. Interestingly, we only found one patient at the initial stage of malaria detection showed PLT decreased, no other unnormal changes in other routine blood results (WBC, ESO) and liver function results (ALT, AST, GGT, TBIL, DBIL, CG) were found from the beginning to end course of the disease. Conclusion COVID-19 infection may promote the resurgence of malaria, so the relapse of malaria should be monitored especially for the patient with malaria infection history who begin to develop fever and other symptoms a few days after the diagnosis of COVID-19. The inflammatory indicators would be worth able as an auxiliary judgment basis for the effective treatment of the two combined infection.
Prion; Viral; Bacterial and Fungal Pathogens of Humans [VV210], Protozoan; Helminth and Arthropod Parasites of Humans [VV220], Diagnosis of Human Disease [VV720], aspartate aminotransferase, clinical aspects, concurrent infections, coronavirus disease 2019, C-reactive protein, diagnosis, disease course, disease markers, falciparum malaria, fever, headaches, hospital admission, human diseases, inflammation, laboratory tests, leukocyte count, leukocytes, lymphocytes, mosquito-borne diseases, protozoal infections, symptoms, viral diseases, parasites, infections, parasitoses, man, Plasmodium falciparum, Severe acute respiratory syndrome coronavirus 2, Protozoa, China, Guangdong, APEC countries, East Asia, Asia, high Human Development Index countries, upper-middle income countries, Central Southern China, Homo, Hominidae, primates, mammals, vertebrates, Chordata, animals, eukaryotes, Plasmodium, Plasmodiidae, Haemospororida, Apicomplexa, Severe acute respiratory syndrome-related coronavirus, Betacoronavirus, Coronavirinae, Coronaviridae, Nidovirales, positive-sense ssRNA Viruses, ssRNA Viruses, RNA Viruses, viruses, GOT, People's Republic of China, clinical picture, disease progression, pyrexia, Kwantung, cell count, leucocytes, white blood cells, protozoal diseases, SARS-CoV-2, viral infections, parasitosis, parasitic diseases, parasitic infestations
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
Chinese
Journal:
China Tropical Medicine
Year:
2023
Document Type:
Article
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