Ceftazidime exhibits a broad inhibition to the infection of SARS-CoV-2 prototype and Omicron variant in vitro by blocking spike protein-ACE2 interaction.

Zheng, Yun-Zhe; Liu, Zhao-Yuan; Li, Yue; Lv, Xiao-Ying; Wu, Yi; Huang, Meng-Wen; Pan, Xing-Chao; Chen, Jian-Feng; Lin, Chang-Dong

Zheng, Yun-Zhe; Liu, Zhao-Yuan; Li, Yue; Lv, Xiao-Ying; Wu, Yi; Huang, Meng-Wen; Pan, Xing-Chao; Chen, Jian-Feng; Lin, Chang-Dong.

Zheng YZ; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Liu ZY; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Li Y; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Lv XY; Fundamental Research Center, Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
Wu Y; Fundamental Research Center, Shanghai YangZhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
Huang MW; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Pan XC; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Chen JF; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China. jfchen@sibcb.ac.cn.
Lin CD; School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China. jfchen@sibcb.ac.cn.

Acta Pharmacol Sin ; 2023 Mar 21.

Article in English | MEDLINE | ID: covidwho-2288889

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Full text: Available Collection: International databases Database: MEDLINE Topics: Variants Language: English Journal subject: Pharmacology Year: 2023 Document Type: Article Affiliation country: S41401-023-01071-0

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