A discussion of heat generation during a fever

Zhou, W.; Liotta, L. A.; Petricoin, E. F.

Zhou, W.; Liotta, L. A.; Petricoin, E. F..

Current Topics in Peptide and Protein Research ; 23:103-106, 2022.

Article in English | EMBASE | ID: covidwho-2288972

ABSTRACT

ABSTRACT

Fever can be caused by pathogen infection. We analyze the thermogenesis mechanism and reveal that heat is naturally generated during the immune system's fight against pathogen infection. Particularly, the heat production by reactive oxygen species that originates in the respiratory burst significantly contributes to the fever development. This analysis can help address mechanisms of SARS-CoV-2 pathogenesis or provide a foundation for future mechanistic inquiries.Copyright © 2022, Research Trends (P) LTD.. All rights reserved.

Keywords

fever, reactive oxygen species, respiratory burst, SARS-CoV-2, thermogenesis, article, human, immune system, nonhuman, plant pathogen interaction, Severe acute respiratory syndrome coronavirus 2, reactive oxygen metabolite

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Collection: Databases of international organizations Database: EMBASE Language: English Journal: Current Topics in Peptide and Protein Research Year: 2022 Document Type: Article

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