Proteomic understanding of SARS-CoV-2 infection and COVID-19: Biological, diagnostic, and therapeutic perspectives
Omics Approaches and Technologies in COVID-19
; : 61-85, 2022.
Article
in English
| Scopus | ID: covidwho-2290843
ABSTRACT
The research community responded rapidly to the SARS-CoV-2 pandemic with a burst of proteomic studies to understand this new virus. We focus in this chapter on proteomic approaches and advances in the areas of the viral proteome and the viral-host protein-protein interactions exploited to facilitate the pathogenic life cycle of SARS-CoV2. We also outline the proteome and posttranslational protein modifications of infected cells and blood proteomics of COVID-19 patients in relation to pathogenesis, host response, and disease severity. Finally, tools and application for COVID-19 proteomics and implementations in diagnostics and therapies are surveyed before summarizing the present achievements and future perspectives. © 2023 Elsevier Inc. All rights reserved.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
Omics Approaches and Technologies in COVID-19
Year:
2022
Document Type:
Article
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