Pulmonary function and functional capacity at 3, 6 and 12 months in COVID-19 patients and effect of physical activity on recovery
Minerva Respiratory Medicine
; 62(1):1-8, 2023.
Article
in English
| EMBASE | ID: covidwho-2291223
ABSTRACT
BACKGROUND:
Long-term sequelae due to Coronavirus disease 2019 (COVID-19) are now under investigation. Aim of this study was to evaluate the one-year clinical impact of COVID-19 on respiratory function and relation with physical activity. METHOD(S) One hundred four patients were evaluated 3, 6 and 12 months after SARS-CoV-2 diagnosis. Clinical conditions, symptomatology, 6-minute walking test (6MWT), pulmonary function test with spirometry and diffusing capacity of carbon monoxide (DLCO) were analyzed. RESULT(S) Eighty-six (82.7%) patients referred at least one symptom at 3 months, 46 (44.2%) at 6 months and 24 (23.1%) at 12 months. At the 3-months visit, patients with moderate COVID showed a slight decrease of distance at the 6MWT, with an improvement at 12 months (P=0.04). Patients with severe COVID-19 showed a recovery of SpO2 at rest (P<0.001), DLCO (P=0.001), DLCO/VA (P=0.002), forced vital capacity (P=0.01) and 6MWT distance (P=0.002) at 6 and 12 months. Patients with critical COVID-19 showed a remarkable reduction of DLCO at 3 months (65+/-21%). Then a subsequent gradual improvement of DLCO was recorded (78+/-18% at 6 months, 85+/-16% at 12 months, P=0.01). Patients with DLCO<80% of predicted at 12 months were older (P=0.02), with higher prevalence of cardio-vascular disease (P=0.006), diabetes (P=0.01) and critical COVID-19 (P=0.003). The improvement of 6MWT distance and DLCO during the three visits did not correlate with physical activity. CONCLUSION(S) Patients with COVID-19 lung involvement showed a progressive improvement in respiratory function and physical performance at 6 and 12 months after acute disease.Copyright © 2022 EDIZIONI MINERVA MEDICA.
Athletes; covid-19; Exercise; Sports; adult; anosmia; article; asthma; cardiovascular disease; chronic kidney failure; chronic obstructive lung disease; coronavirus disease 2019; coughing; diffusing capacity for carbon monoxide; dizziness; dyspnea; female; fever; functional status; headache; human; hypertension; intensive care unit; international physical activity questionnaire; lung embolism; major clinical study; malaise; male; maximal voluntary ventilation; middle aged; myalgia; nausea; obesity; oxygen saturation; physical activity; pneumonia; Pneumonia Severity Index; six minute walk test; sore throat; vomiting; weakness; pulse oximeter; BlueNight
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Experimental Studies
Language:
English
Journal:
Minerva Respiratory Medicine
Year:
2023
Document Type:
Article
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