Clinical case analysis of novel coronavirus pneumonia complicated with pulmonary hypertension.
Adverse Drug Reactions Journal
; 22(6):355-359, 2020.
Article
in Chinese
| EMBASE | ID: covidwho-2291790
ABSTRACT
Objective:
To report the clinical features of pulmonary hypertension diagnosed by echocardiography in 5 patients with novel coronavirus pneumonia (COVID-19) in order to understand the special clinical manifestations of COVID-19 and explore the possible mechanism. Method(s) The echocardiographic data and clinical characteristics of COVID-19 patients complicated with pulmonary hypertension diagnosed by echocardiography in Beijing Ditan Hospital, Capital Medical University were analyzed descriptively from February 5 to March 31, 2020. Result(s) A total of 15 patients with severe and critical COVID-19 patients underwent echocardiography. Of them, 7 patients were diagnosed with pulmonary hypertension, 5 of which were confirmed as complications of COVID-19. Among the 5 patients, 4 were female and 1 was male, aged 62-78 years;4 were with hypertension, 3 were with diabetes, and 1 was with coronary atherosclerotic heart disease. All 5 critically ill patients with COVID-19 were given ventilator-assisted breathing, 2 of which were given extracorporeal membrane oxygenation at the same time. According to echocardiography, the systolic pressure of pulmonary artery in 5 patients was 43-65 mmHg, with an average of 54 mmHg. The severity of pulmonary hypertension was graded as mild in 1 patient and moderate in 4 patients. During the follow-up, pulmonary artery systolic pressure gradually decreased to normal in 4 patients, and then ventilator and ECMO were withdrawn;1 patient died due to respiratory failure and persistent pulmonary hypertension. Conclusion(s) Patients with COVID-19 may be complicated by pulmonary hypertension, which is often found in the critical patients. Echocardiography is an important imagingdiagnostic method for pulmonary hypertension in patients with COVID-19.Copyright © 2020 by the Chinese Medical Association.
Coronavirus infections; Echocardiography; Hypertension; pulmonary; adult; aged; article; clinical article; clinical feature; coronary atherosclerosis; coronavirus disease 2019; critically ill patient; diabetes mellitus; disease severity; extracorporeal oxygenation; female; follow up; human; hypertension; male; middle aged; mortality; mortality rate; persistent pulmonary hypertension; priority journal; pulmonary artery systolic pressure; pulmonary hypertension/co [Complication]; pulmonary hypertension/di [Diagnosis]; respiratory failure; systolic blood pressure; university hospital; mechanical ventilator
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Prognostic study
Language:
Chinese
Journal:
Adverse Drug Reactions Journal
Year:
2020
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS