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Overview of the cardio-metabolic impact of the COVID-19 pandemic.
Barkhordarian, Maryam; Behbood, Arezoo; Ranjbar, Maryam; Rahimian, Zahra; Prasad, Anand.
  • Barkhordarian M; Department of Medicine, Division of Cardiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
  • Behbood A; MPH department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.
  • Ranjbar M; Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.
  • Rahimian Z; Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.
  • Prasad A; Division of Cardiology, Department of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. PrasadA@uthscsa.edu.
Endocrine ; 80(3): 477-490, 2023 Jun.
Article in English | MEDLINE | ID: covidwho-2291939
ABSTRACT
Evidence has shown that cardiometabolic disorders (CMDs) are amongst the top contributors to COVID-19 infection morbidity and mortality. The reciprocal impact of COVID-19 infection and the most common CMDs, the risk factors for poor composite outcome among patients with one or several underlying diseases, the effect of common medical management on CMDs and their safety in the context of acute COVID-19 infection are reviewed. Later on, the changes brought by the COVID-19 pandemic quarantine on the general population's lifestyle (diet, exercise patterns) and metabolic health, acute cardiac complications of different COVID-19 vaccines and the effect of CMDs on the vaccine efficacy are discussed. Our review identified that the incidence of COVID-19 infection is higher among patients with underlying CMDs such as hypertension, diabetes, obesity and cardiovascular disease. Also, CMDs increase the risk of COVID-19 infection progression to severe disease phenotypes (e.g. hospital and/or ICU admission, use of mechanical ventilation). Lifestyle modification during COVID-19 era had a great impact on inducing and worsening of CMDs. Finally, the lower efficacy of COVID-19 vaccines was found in patients with metabolic disease.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Endocrine Journal subject: Endocrinology Year: 2023 Document Type: Article Affiliation country: S12020-023-03337-3

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Endocrine Journal subject: Endocrinology Year: 2023 Document Type: Article Affiliation country: S12020-023-03337-3