Viral Hepatitis and Acute-on-Chronic Liver Failure.
Clin Liver Dis
; 27(3): 617-630, 2023 08.
Article
in English
| MEDLINE | ID: covidwho-2292276
ABSTRACT
Acute-on-chronic liver failure (ACLF) is a potentially reversible syndrome that develops in patients with cirrhosis or with underlying chronic liver disease (CLD) and is characterized by acute decompensation, organ failure, and high short-term mortality. Hepatitis A and hepatitis E are major causes of ACLF. Hepatitis B may also cause ACLF through a flare of hepatitis B, acute infection, or reactivation. Besides supportive care, nucleoside/nucleotide analog therapy should also be initiated in this setting. Nonhepatotropic viruses may rarely also cause ACLF with the severe acute respiratory syndrome coronavirus 2 virus recently being identified with poorer outcomes in those with underlying CLD.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Hepatitis E
/
Acute-On-Chronic Liver Failure
/
COVID-19
/
Hepatitis B
Limits:
Humans
Language:
English
Journal:
Clin Liver Dis
Journal subject:
Gastroenterology
Year:
2023
Document Type:
Article
Affiliation country:
J.cld.2023.03.006
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