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Successful Treatment of Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Patients With Immunodeficiency With Extended Nirmatrelvir/Ritonavir: Case Series.
Breeden, Madison; Aitken, Samuel L; Baang, Ji Hoon; Gravelin, Misty; Kaul, Daniel R; Lauring, Adam S; Petty, Lindsay A; Gregg, Kevin S.
  • Breeden M; Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Aitken SL; Department of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.
  • Baang JH; Department of Clinical Pharmacy, University of Michigan College of Pharmacy, Ann Arbor, Michigan, USA.
  • Gravelin M; Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Kaul DR; Michigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, Michigan, USA.
  • Lauring AS; Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Petty LA; Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Gregg KS; Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Open Forum Infect Dis ; 10(4): ofad189, 2023 Apr.
Article in English | MEDLINE | ID: covidwho-2292576
ABSTRACT
Immunocompromised patients with B-cell deficiencies are at risk for prolonged symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We describe 4 patients treated for B-cell malignancies with B-cell-depleting therapies who developed persistent SARS-CoV-2 infection and had resolution of symptoms following an extended course of nirmatrelvir/ritonavir.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Long Covid Language: English Journal: Open Forum Infect Dis Year: 2023 Document Type: Article Affiliation country: Ofid

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Topics: Long Covid Language: English Journal: Open Forum Infect Dis Year: 2023 Document Type: Article Affiliation country: Ofid