Triple Positive Antiphospholipid Antibody Syndrome in Pregnancy with High Frequency Plasma Exchange: A Case Report.
Transfus Med Hemother
; 50(2): 154-158, 2023 Apr.
Article
in English
| MEDLINE | ID: covidwho-2293692
ABSTRACT
Introduction:
Triple antibody positive antiphospholipid syndrome during pregnancy carries a poor prognosis. The placental vasculature is particularly vulnerable to these antibodies resulting in a marked increased risk of fetal growth restriction, placental infarction, abruption, stillbirth, and preterm severe preeclampsia. Case Presentation We report a case of a primigravida with triple antibody positive antiphospholipid syndrome that demonstrated placental insufficiency and fetal compromise at a previable gestation. The patient underwent plasma exchange every 48 h for 11 weeks resulting in delivery of a viable infant. Placental blood flow was improved after complete absence of end-diastolic flow in the fetal umbilical artery.Conclusion:
Scheduled plasmapheresis every 48 h can be considered in select cases of antiphospholipid antibody syndrome.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Case report
/
Prognostic study
Language:
English
Journal:
Transfus Med Hemother
Year:
2023
Document Type:
Article
Affiliation country:
000526349
Similar
MEDLINE
...
LILACS
LIS