Case report: Hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis.
Front Med (Lausanne)
; 9: 1096900, 2022.
Article
in English
| MEDLINE | ID: covidwho-2294040
ABSTRACT
Hemophagocytic lymphohistiocytosis may occur in patients with genetic predisposition and in sporadic cases due to malignancy or infection. We describe a 49-year old man with hemorrhagic fever, type 1 respiratory insufficiency and acute kidney injury. Diagnostic work up showed a hyperinflammatory syndrome, hypertriglyceridemia, hemophagocytosis, very high ferritin and significantly elevated sCD25. The findings were compatible with hemophagocytic lymphohistiocytosis based on the HLH-2004 criteria. Serological testing indentified Puumala virus as the causal pathogen. The patient was successfully treated with pulse corticosteroids, intravenous immunoglobins and supportive therapy.
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MEDLINE
Type of study:
Case report
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Diagnostic study
Language:
English
Journal:
Front Med (Lausanne)
Year:
2022
Document Type:
Article
Affiliation country:
Fmed.2022.1096900
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