Acute kidney injury in patient with severe SARS-CoV-2 infection.
Medecine Intensive Reanimation
; 30:43-52, 2021.
Article
in French
| EMBASE | ID: covidwho-2295250
ABSTRACT
Acute kidney injury (AKI) during SARS-CoV-2 infection is frequent and associated with mortality. Pathophysiology of AKI is multifactorial, and encompasses direct (viral invasion, endothelitis and thrombosis, renin-angiotensin-aldosteron system activation, cytokine elevation) and undirect mechanisms (hemodynamic instability, effect of mechanical ventilation, nephrotoxic medications). Acute tubular necrosis is the most frequent histological lesion identified, but glomerular disease can also be observed. To date, there is no specific treatment of SARS-CoV-2 induced AKI.Copyright © SRLF 2021.
Acute kidney injury; covid-19; intensive care unit; acute kidney tubule necrosis; adult; article; artificial ventilation; controlled study; coronavirus disease 2019; endotheliitis; glomerulopathy; hemodynamics; histopathology; human; mortality; nephrotoxicity; nonhuman; renin angiotensin aldosterone system; Severe acute respiratory syndrome coronavirus 2; side effect; thrombosis; cytokine; endogenous compound
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
French
Journal:
Medecine Intensive Reanimation
Year:
2021
Document Type:
Article
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