Covid-19-associated diffuse posthypoxic leukoencephalopathy and microhemorrhages - A case report
Neuroimmunology Reports
; 2 (no pagination), 2022.
Article
in English
| EMBASE | ID: covidwho-2295389
ABSTRACT
Background:
Delayed post-hypoxic leukoencephalopathy (DPHL) with associated microbleeds is a clinical entity presenting with cognitive impairment days or weeks after an episode of acute hypoxic brain injury. Case report We describe a 68-year-old male with SARS-CoV2 infection who had cardiac arrest, required sedation and mechanical ventilation for 17 days, and after sedation was discontinued, he became unresponsive. Brain MRI showed diffuse confluent hyperintense signals in the subcortical white matter and multiple subcortical white matter microhemorrhages. EEG revealed diffuse attenuation of brain electrical activity with isolated polymorphic delta waves in the frontal region without epileptiform activity. Conclusion(s) Clinicians need to be aware that patients with Covid-19 can develop delayed post-hypoxic leukoencephalopathy.Copyright © 2022 The Authors
Leukoencephalopathies; Microhemorrhages; Neurological complication; SARS-CoV-2; aged; article; artificial ventilation; brain hemorrhage/co [Complication]; brain hemorrhage/di [Diagnosis]; case report; clinical article; clinical feature; coronavirus disease 2019/di [Diagnosis]; delta rhythm; disease association; frontal cortex; heart arrest/di [Diagnosis]; human; leukoencephalopathy/co [Complication]; leukoencephalopathy/di [Diagnosis]; male; neuroimaging; nuclear magnetic resonance imaging; sedation; treatment duration; white matter; delayed posthypoxic leukoencephalopathy/co [Complication]; delayed posthypoxic leukoencephalopathy/di [Diagnosis]
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Case report
Language:
English
Journal:
Neuroimmunology Reports
Year:
2022
Document Type:
Article
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