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Chemistry towards Biology-Instruct: Snapshot.
Hricovíni, Milos; Owens, Raymond J; Bak, Andrzej; Kozik, Violetta; Musial, Witold; Pierattelli, Roberta; Májeková, Magdaléna; Rodríguez, Yoel; Musiol, Robert; Slodek, Aneta; Starha, Pavel; Pietak, Karina; Slota, Dagmara; Florkiewicz, Wioletta; Sobczak-Kupiec, Agnieszka; Jampílek, Josef.
  • Hricovíni M; Institute of Chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 845 38 Bratislava, Slovakia.
  • Owens RJ; Structural Biology, The Rosalind Franklin Institute, Harwell Science Campus, UK, University of Oxford, Oxford OX11 0QS, UK.
  • Bak A; Division of Structural Biology, The Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Kozik V; Institute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.
  • Musial W; Institute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.
  • Pierattelli R; Department of Physical Chemistry and Biophysics, Pharmaceutical Faculty, Wroclaw Medical University, Borowska 211A, 50 556 Wroclaw, Poland.
  • Májeková M; Magnetic Resonance Center and Department of Chemistry "Ugo Schiff", University of Florence, 50019 Sesto Fiorentino, Italy.
  • Rodríguez Y; Center of Experimental Medicine SAS and Department of Biochemical Pharmacology, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dubravska cesta 9, 841 04 Bratislava, Slovakia.
  • Musiol R; Department of Natural Sciences, Eugenio María de Hostos Community College, City University of New York, 500 Grand Concourse, Bronx, NY 10451, USA.
  • Slodek A; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA.
  • Starha P; Institute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.
  • Pietak K; Institute of Chemistry, University of Silesia, Szkolna 9, 40 007 Katowice, Poland.
  • Slota D; Department of Inorganic Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 1192/12, 771 46 Olomouc, Czech Republic.
  • Florkiewicz W; Department of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawla II Av., 31 864 Krakow, Poland.
  • Sobczak-Kupiec A; Department of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawla II Av., 31 864 Krakow, Poland.
  • Jampílek J; Department of Materials Science, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawla II Av., 31 864 Krakow, Poland.
Int J Mol Sci ; 23(23)2022 Nov 26.
Article in English | MEDLINE | ID: covidwho-2296638
ABSTRACT
The knowledge of interactions between different molecules is undoubtedly the driving force of all contemporary biomedical and biological sciences. Chemical biology/biological chemistry has become an important multidisciplinary bridge connecting the perspectives of chemistry and biology to the study of small molecules/peptidomimetics and their interactions in biological systems. Advances in structural biology research, in particular linking atomic structure to molecular properties and cellular context, are essential for the sophisticated design of new medicines that exhibit a high degree of druggability and very importantly, druglikeness. The authors of this contribution are outstanding scientists in the field who provided a brief overview of their work, which is arranged from in silico investigation through the characterization of interactions of compounds with biomolecules to bioactive materials.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Molecular Biology Language: English Year: 2022 Document Type: Article Affiliation country: Ijms232314815

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Molecular Biology Language: English Year: 2022 Document Type: Article Affiliation country: Ijms232314815