Comparative analysis in resolving the symptoms in patients with laryngitis posterior treated with PPI and levocitirizine and PPI and desloratadine

ABSTRACT

Background: Living in a covid 19 pandemic lockdown, and the "new normal" over all, is a stressful situation for all of us. As an ENT specialist I confronted a higher incidence of laryngitis posterior and GERD patients amoung the patients with previous allergic diathesis from March 2020 until December 2020 compared with the previous years. Method(s) Two different treatments of the patients with laryngitis posterior and GER patients in the clinical hospital of Bitola, between March 2020 and December 2020. The first treatment consists of esomeprazole and levocitirizine, and the second consists of esomeprazole and desloratadine. These treatments were applied to two different groups -first group comprising 24 patients, and the second one comprising 29 patients. The follow up was a month after a given therapy. Result(s) All the patients were evaluated a month after treatment. First part of the evaluation was subjective and the patients had to answer if they are feeling better on the scale from 1 to 5. The second part was fiberlaryngoscopy and the evaluation of the interarytenoid space. Only 15% (3 patients) of the first group were feeling completely good, and 34% (10 patients) from the second group. The finding of laryngoscopy and evaluation of the interarytenoide space was without hyperemia and oedema in 50% (12 patients) from the first group and 69% (20 patients) in the second group. Conclusion(s) The comparison of the results of the two groups shows that the patients in the second group, treated with esomeprazole and desloratadin are feeling better more than twice from the first group, and for almost more than 20% have no more hyperemia and oedema compared to the first group. In order to enhance the results of the patients' treatment further follow up all patients is necessary.