Oxygen markers for predicting COVID-19 - related pneumonia mortality
Revista Informacion Cientifica
; 101(6), 2022.
Article
in Spanish
| CAB Abstracts | ID: covidwho-2298662
ABSTRACT
Introduction:
the value of oxygen as a prognostic maker of mortality due to COVID-19 pneumonia has not been evaluated at the Hospital General Docente "Dr. Agostinho Neto".Background:
to identify the values of oxygenation markers for prognosing mortality caused by COVID-19 pneumonia at the Hospital General Docente "Dr. Agostinho Neto" de Guantanamo, Cuba, throughout period 2020-2021.Method:
a cohort of 276 patients with COVID-19 pneumonia was studied. Peripheral oxygen saturation (SpO2), arterial oxygen saturation (SaO2), the difference between the oxygen concentration in the alveoli and arterial system (DA-aO2), arterial oxygen pressure ratio (PaO2) and inspired oxygen fraction (FiO2) [PaO2/FiO2] were studied. The association between variables and deceased discharge was determined using the Chi-square technique and the Odds Ratio (OR) calculation.Results:
the variable with the highest positive predictive value was SpO2 (87.3%) with a value lower than 90 mmHg at admission. The highest negative predictive value was recorded for the DA-aO2 variable (95.6%), less than 20 mmHg at 48 hours after admission. Attributable risk was higher for PaO2/FiO2 ratio, less than 300 mmHg (0.59), at admission (0.52). Attributable risk percent was higher for the variable DA-aO2 20 mmHg at admission (95.8%) and at 48 hours after admission (95.3%).Conclusions:
abnormal DA-aO2, PaO2/FiO2 ratio, SaO2 and SpO2, at admission and 48 hours after admission, are predictive markers of mortality in patients with COVID-19.
Prion; Viral; Bacterial and Fungal Pathogens of Humans [VV210]; human diseases; oxygen; bronchopneumonia; hypoxia; respiratory diseases; morbidity; mortality; pneumonia; coronavirus disease 2019; man; Severe acute respiratory syndrome coronavirus 2; Cuba; Africa South of Sahara; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Greater Antilles; Antilles; Caribbean; America; high Human Development Index countries; Latin America; upper-middle income countries; Africa; SARS-CoV-2; subsaharan Africa; lung diseases; death rate
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Prognostic study
Language:
Spanish
Journal:
Revista Informacion Cientifica
Year:
2022
Document Type:
Article
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