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The main protease of SARS-CoV-2 downregulates innate immunity via a translational repression.
Liang, Weifeng; Gu, Ming; Zhu, Lingxiang; Yan, Ziqi; Schenten, Dominik; Herrick, Shelby; Li, Hongmin; Samrat, Subodh Kumar; Zhu, Jiapeng; Chen, Yin.
  • Liang W; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, China.
  • Gu M; Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.
  • Zhu L; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210023, China.
  • Yan Z; Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.
  • Schenten D; Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.
  • Herrick S; Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.
  • Li H; Department of Immunology, School of Medicine, The University of Arizona, Tucson, AZ, 85724, USA.
  • Samrat SK; Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.
  • Zhu J; Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.
  • Chen Y; Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona, Tucson, AZ, 85721, USA.
Signal Transduct Target Ther ; 8(1): 162, 2023 04 13.
Article in English | MEDLINE | ID: covidwho-2298825
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2023 Document Type: Article Affiliation country: S41392-023-01418-3

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2023 Document Type: Article Affiliation country: S41392-023-01418-3