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Severe community-acquired pneumonia.
Niederman, Michael S; Torres, Antoni.
  • Niederman MS; Division of Pulmonary and Critical Care Medicine, New York Presbyterian/Weill Cornell Medical Center, Weill Cornell Medical College, New York, NY, USA.
  • Torres A; Both authors contributed equally.
Eur Respir Rev ; 31(166)2022 Dec 31.
Article in English | MEDLINE | ID: covidwho-2300932
ABSTRACT
Severe community-acquired pneumonia is the most life-threatening form of community-acquired pneumonia, characterised by intensive care unit admission and high morbidity and mortality. In this review article, we cover in depth six aspects of severe community-acquired pneumonia that are still controversial use of PCR molecular techniques for microbial diagnosis; the role of biomarkers for initial management; duration of treatment, macrolides or quinolones in the initial empirical antibiotic therapy; the use of prediction scores for drug-resistant pathogens to modify initial empiric therapy; the use of noninvasive mechanical ventilation and high-flow nasal oxygen; and the use of corticosteroids as adjunctive therapy in severe community-acquired pneumonia.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / Community-Acquired Infections Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: 16000617.0123-2022

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia / Community-Acquired Infections Type of study: Diagnostic study / Prognostic study Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: 16000617.0123-2022