Coronavirus genomic cDNA derived G-quadruplex as a selective target for fluorometric detection.
Chem Commun (Camb)
; 59(38): 5717-5720, 2023 May 09.
Article
in English
| MEDLINE | ID: covidwho-2302030
ABSTRACT
Pathogenic genomes harboring noncanonical G-quadruplex (GQ) forming sequences are potential targets for diagnosis. The GQ-forming cDNA sequences of SARS-CoV-2 (Severe acute respiratory syndrome coronavirus-2) are identified and validated as reliable diagnostic targets. The high fidelity fluorescence detection of specific cDNA GQs derived from the SARS-CoV-2 RNA genome is demonstrated using small molecular probes.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
G-Quadruplexes
/
COVID-19
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Chem Commun (Camb)
Journal subject:
Chemistry
Year:
2023
Document Type:
Article
Affiliation country:
D3cc00740e
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