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Long-term humoral response following Delta and Omicron BA.1 co-infection.
Saade, Carla; Pozzetto, Bruno; Yaugel-Novoa, Melyssa; Oriol, Guy; Josset, Laurence; Lina, Bruno; Paul, Stéphane; Bal, Antonin; Trouillet-Assant, Sophie.
  • Saade C; CIRI-Centre International de Recherche en Infectiologie, Université Claude Bernard Lyon 1, Inserm, U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, 69007, France.
  • Pozzetto B; CIRI-Centre International de Recherche en Infectiologie, Université Claude Bernard Lyon 1, Inserm, U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, 69007, France.
  • Yaugel-Novoa M; Immunology Laboratory, CIC1408, CHU Saint-Etienne, Saint-Etienne, 42055, France.
  • Oriol G; CIRI-Centre International de Recherche en Infectiologie, Université Claude Bernard Lyon 1, Inserm, U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, 69007, France.
  • Josset L; Joint Research Unit Civils Hospices of Lyon-bioMérieux, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite, 69310, France.
  • Lina B; CIRI-Centre International de Recherche en Infectiologie, Université Claude Bernard Lyon 1, Inserm, U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, 69007, France.
  • Paul S; Laboratoire de Virologie, Institut des Agents Infectieux, Centre National de Référence des virus des infections respiratoires, Hospices Civils de Lyon, F-69004, Lyon, France.
  • Bal A; GenEPII Sequencing Platform, Institut des Agents Infectieux, Hospices Civils de Lyon, F-69004, Lyon, France.
  • Trouillet-Assant S; CIRI-Centre International de Recherche en Infectiologie, Université Claude Bernard Lyon 1, Inserm, U1111, CNRS, UMR5308, ENS Lyon, Université Jean Monnet de Saint-Etienne, Lyon, 69007, France.
NPJ Vaccines ; 8(1): 57, 2023 Apr 20.
Article in English | MEDLINE | ID: covidwho-2302870
ABSTRACT
This study reports the 6-month humoral immune response in vaccinated patients concomitantly infected with Delta and Omicron BA.1 variants of SARS-CoV-2. Interestingly, the simultaneous exposure to the Delta and BA.1 S proteins does not confer an additional immune advantage compared to exposure to the BA.1 S protein alone.
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Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines / Variants Language: English Journal: NPJ Vaccines Year: 2023 Document Type: Article Affiliation country: S41541-023-00652-8

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Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines / Variants Language: English Journal: NPJ Vaccines Year: 2023 Document Type: Article Affiliation country: S41541-023-00652-8