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Impact of the Early COVID-19 Pandemic on the Number of HIV Preexposure Prophylaxis Uses and the Proportion of Preexposure Prophylaxis Users Receiving Sexually Transmitted Infection Testing Services.
Schmidt, Mark A; Salas, Suzanne B; Donald, Judy L; Gift, Thomas L; Tao, Guoyu.
  • Schmidt MA; From the Center for Health Research, Kaiser Permanente Northwest, Portland, OR.
  • Salas SB; From the Center for Health Research, Kaiser Permanente Northwest, Portland, OR.
  • Donald JL; From the Center for Health Research, Kaiser Permanente Northwest, Portland, OR.
  • Gift TL; Centers for Disease Control and Prevention, Atlanta, GA.
  • Tao G; Centers for Disease Control and Prevention, Atlanta, GA.
Sex Transm Dis ; 50(5): 304-309, 2023 05 01.
Article in English | MEDLINE | ID: covidwho-2303267
ABSTRACT

BACKGROUND:

With the potential impact of the COVID-19 pandemic on HIV preexposure prophylaxis (PrEP) care management, we assessed the number of PrEP users and sexually transmitted infection (STI) testing-eligible PrEP users, STI testing rates, and prevalence between prepandemic (January 1, 2018-March 31, 2020) and early-pandemic (April 1, 2020-September 30, 2020) periods.

METHODS:

In this retrospective cohort study, a PrEP user for a given quarter is defined as either a previous PrEP user or a PrEP initiator who has at least 1-day coverage of tenofovir/emtricitabine in the given quarter. The STI testing-eligible PrEP users for a given quarter were defined as those persons whose runout date (previous dispense date + days of tenofovir/emtricitabine supply) was in the given quarter.

RESULTS:

The quarterly number of PrEP users increased from the first quarter of 2018 to the first quarter of 2020 and then decreased in the second and third quarter of 2020. Among STI testing-eligible PrEP users who had ≤14 days between runout and next refill date, gonorrhea and chlamydia screening testing rates were 95.1% for prepandemic and 93.4% for early pandemic ( P = 0.1011). Among all STI testing-eligible PrEP users who were tested for gonorrhea and chlamydia, gonorrhea prevalence was 6.7% for prepandemic and 5.7% for early pandemic ( P = 0.3096), and chlamydia prevalence was 7.0% for prepandemic and 5.8% for early pandemic ( P = 0.2158).

CONCLUSIONS:

Although the early COVID-19 pandemic resulted in lower numbers of PrEP users and PrEP initiators, individuals who remained continuous users of PrEP maintained extremely high rates of bacterial STI screening. With high STI prevalence among PrEP users, assessments of PrEP care management are continuously needed.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Gonorrhea / Sexually Transmitted Diseases / HIV Infections / Pre-Exposure Prophylaxis / COVID-19 Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Variants Limits: Humans / Male Language: English Journal: Sex Transm Dis Year: 2023 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Gonorrhea / Sexually Transmitted Diseases / HIV Infections / Pre-Exposure Prophylaxis / COVID-19 Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study Topics: Variants Limits: Humans / Male Language: English Journal: Sex Transm Dis Year: 2023 Document Type: Article