The current state of knowledge about COVID-19 vaccines during pregnancy

ABSTRACT

More than a year since the start of the COVID-19 pandemic, the global administration of the COVID-19 vaccines hopes to confer sustained protection against SARS-CoV-2 and stop this difficult to predict situation. They are highly effective, especially at preventing the severe form of disease and reducing the death rate from COVID-19. Pregnant women represent a high-risk category of population for infectious diseases, including COVID-19, and need to be considered for vaccination. Because the results of clinical trials of COVID-19 vaccines in pregnant women are not yet published, many questions remain to be answered. There are now available data and information in real-life data, including healthcare pregnant women or in women who did not know they were pregnant at the time of vaccination. This work aims to present the current state of knowledge about COVID-19 vaccines during pregnancy based on reported cases from medical literature. These cases of COVID-19 vaccination will be more and more, and in the future, we will be supplementarily adding data about the benefits and effects of vaccination on pregnancy, fetal and infant development, and their immunity. Today we affirm anti-COVID-19 vaccines during pregnancy are reported to be as safe and effective as in the general population. Because a higher rate of miscarriage in early pregnancy has been observed to be associated with COVID-19, it may seem sagacious to recommend vaccination before planning a pregnancy to gain immunity at the time of conception.Copyright © 2021.