Sotrovimab restores neutralisation against current Omicron subvariants in patients with blood cancer

Wu, Mary Y.; Shepherd, Scott T. C.; Fendler, Annika; Carr, Edward J.; Au, Lewis; Harvey, Ruth; Dowgier, Giulia; Hobbs, Agnieszka; Herman, Lou S.; Ragno, Martina; Adams, Lorin; Schmitt, Andreas M.; Tippu, Zayd; Shum, Benjamin; Farag, Sheima; Rogiers, Aljosja; O'Reilly, Nicola; Bawumia, Philip; Smith, Callie; Carlyle, Eleanor; Edmonds, Kim; Del Rosario, Lyra; Lingard, Karla; Mangwende, Mary; Holt, Lucy; Ahmod, Hamid; Korteweg, Justine; Foley, Tara; Barber, Taja; Hepworth, Stephanie; Emslie-Henry, Andrea; Caulfield-Lynch, Niamh; Byrne, Fiona; Deng, Daqi; Williams, Bryan; Brown, Michael; Caidan, Simon; Gavrielides, Mike; MacRae, James I.; Kelly, Gavin; Peat, Kema; Kelly, Denise; Murra, Aida; Kelly, Kayleigh; O'Flaherty, Molly; Popat, Sanjay; Yousaf, Nadia; Jhanji, Shaman; Tatham, Kate; Cunningham, David; Van As, Nicholas; Young, Kate; Furness, Andrew J. S.; Pickering, Lisa; Beale, Rupert; Swanton, Charles; Gandhi, Sonia; Gamblin, Steve; Bauer, David L. V.; Kassiotis, George; Howell, Michael; Walker, Susanna; Nicholson, Emma; Larkin, James; Wall, Emma C.; Turajlic, Samra

Wu, Mary Y.; Shepherd, Scott T. C.; Fendler, Annika; Carr, Edward J.; Au, Lewis; Harvey, Ruth; Dowgier, Giulia; Hobbs, Agnieszka; Herman, Lou S.; Ragno, Martina; Adams, Lorin; Schmitt, Andreas M.; Tippu, Zayd; Shum, Benjamin; Farag, Sheima; Rogiers, Aljosja; O'Reilly, Nicola; Bawumia, Philip; Smith, Callie; Carlyle, Eleanor; Edmonds, Kim; Del Rosario, Lyra; Lingard, Karla; Mangwende, Mary; Holt, Lucy; Ahmod, Hamid; Korteweg, Justine; Foley, Tara; Barber, Taja; Hepworth, Stephanie; Emslie-Henry, Andrea; Caulfield-Lynch, Niamh; Byrne, Fiona; Deng, Daqi; Williams, Bryan; Brown, Michael; Caidan, Simon; Gavrielides, Mike; MacRae, James I.; Kelly, Gavin; Peat, Kema; Kelly, Denise; Murra, Aida; Kelly, Kayleigh; O'Flaherty, Molly; Popat, Sanjay; Yousaf, Nadia; Jhanji, Shaman; Tatham, Kate; Cunningham, David; Van As, Nicholas; Young, Kate; Furness, Andrew J. S.; Pickering, Lisa; Beale, Rupert; Swanton, Charles; Gandhi, Sonia; Gamblin, Steve; Bauer, David L. V.; Kassiotis, George; Howell, Michael; Walker, Susanna; Nicholson, Emma; Larkin, James; Wall, Emma C.; Turajlic, Samra.

Cancer cell ; 2023.

Article in English | EuropePMC | ID: covidwho-2305848

ABSTRACT

ABSTRACT

Wu et al. report that patients with hematologic malignancies have reduced immunity against SARS-CoV-2 Omicron subvariants and Sotrovimab retains neutralizing capacity against all tested Omicron subvariants.

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Collection: Databases of international organizations Database: EuropePMC Topics: Variants Language: English Journal: Cancer cell Year: 2023 Document Type: Article

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Collection: Databases of international organizations Database: EuropePMC Topics: Variants Language: English Journal: Cancer cell Year: 2023 Document Type: Article