The pre-analytical process management status and influencing factors of laboratory test before prescribing antimicrobial in developing country.
BMC Health Serv Res
; 23(1): 283, 2023 Mar 25.
Article
in English
| MEDLINE | ID: covidwho-2306543
ABSTRACT
INTRODUCTION:
The results of laboratory testing are crucial basis for clinicians to prescribe antimicrobial. Laboratory testing is a highly complex process, and increasing evidence suggests that errors and obstacles in the pre-analytical process (PP) will affect reasonable antimicrobial use. However, PP was an easily neglected link in hospital infection management and the current situation of it and the influencing factors of management are not clear.METHODS:
A cross-sectional survey was conducted in the department of clinical, specimen collection, transportation, and inspection in 109 secondary and tertiary hospitals in Central China. The rate of antimicrobial susceptibility test request (AST) and related indexes of above departments were calculated to describe the situation. Management characteristics (frequency of training etc.) were described as proportions and fractional probit regression analysis was used to determine the influencing factors.RESULTS:
The average rate of non restricted-use antimicrobial was 63%, the restricted-use was 86%, the special-use was 95%. The zero obstacle rate of specimen collection was 27.3%, of specimen transportation was 19.4% and of inspection feedback was 61.7%. There was a difference between the secondary and tertiary hospitals on non restricted-use (X2 = 22.968, P < 0.001); restricted-use (X2 = 29.466, P < 0.001); special-use (X2 = 27.317, P < 0.001). Taking non restricted-use as an example, training (OR = 0.312, 95%CI 0.148,0.429), low-frequency appraisal (OR = 0.153, 95%CI 0.082,0.224), guidance (OR = 0.32, 95%CI 0.237,0.403) and information technology (OR = 0.104, 95%CI 0.009,0.199) were positive factors.CONCLUSIONS:
There were substantial differences in the rate of AST request in clinical department between secondary and tertiary hospitals. The zero obstacle rate in collection, transportation and inspection department were still low. In most departments, training and performance appraisal were positive factors, guidance and information technology were positive supporting factors.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Developing Countries
/
Anti-Infective Agents
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Humans
Language:
English
Journal:
BMC Health Serv Res
Journal subject:
Health Services Research
Year:
2023
Document Type:
Article
Affiliation country:
S12913-023-09243-8
Similar
MEDLINE
...
LILACS
LIS