Influence of influenza vaccine and comorbidity on the evolution of hospitalized COVID-19 patients. / Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19.
Med Clin (Barc)
; 158(12): 603-607, 2022 06 24.
Article
in English, Spanish
| MEDLINE | ID: covidwho-2308996
ABSTRACT
BACKGROUND AND OBJECTIVE:
The COVID-19 coronavirus disease outbreak is evolving around the world. The aim of this study is to evaluate the association between influenza vaccination and the risk of mortality in hospitalized COVID-19 patients, as well as other risk factors. MATERIALS ANDMETHODS:
Retrospective observational study. This study was conducted among hospitalized patients with COVID-19 at Hospital La Mancha Centro between March 5 and 25, 2020. Information on influenza vaccination was extracted from electronic medical records. We used a multivariate logistic regression to explore the association between influenza vaccination and mortality from COVID and other risk factors.RESULTS:
410 patients were included. Influenza vaccine had no effect among COVID-19 hospitalized patients [OR 1.55 (95%CI 0.96 - 2.48; p=0.071)]. Increasing hospital mortality was associated with older age [OR 1.05 (95% CI 1.02-1.07), per year increase; p<0.001)], Charlson ≥3 [OR 1.84 (95%CI 1.07-3.15, p=0.027)] and heart failure on admission [OR 6 (IC95% 1.6 - 21.7; p=0.007)]CONCLUSIONS:
Influenza vaccine had no effect among COVID-19 hospitalized patients. The risk factors identified were older age, higher comorbidity and heart failure on admission.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Influenza Vaccines
/
Influenza, Human
/
COVID-19
/
Heart Failure
Type of study:
Case report
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Humans
Language:
English
/
Spanish
Journal:
Med Clin (Barc)
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS