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COVID-19 Infection and Acute Pancreas Transplant Graft Thrombosis.
Mathuram Thiyagarajan, Umasankar; Dajani, Khaled; Anderson, Blaire; Bigam, David; James Shapiro, A M.
  • Mathuram Thiyagarajan U; Department of Hepatobiliary and Pancreatic Surgery and Transplantation, University of Alberta Hospital, Edmonton, CAN.
  • Dajani K; Department of Hepatobiliary and Pancreatic Surgery and Transplantation, University of Alberta Hospital, Edmonton, CAN.
  • Anderson B; Department of Hepatobiliary and Pancreatic Surgery and Transplantation, University of Alberta Hospital, Edmonton, CAN.
  • Bigam D; Department of Hepatobiliary and Pancreatic Surgery and Transplantation, University of Alberta Hospital, Edmonton, CAN.
  • James Shapiro AM; Department of Surgery, Medicine, and Surgical Oncology, University of Alberta Hospital, Edmonton, CAN.
Cureus ; 15(1): e34087, 2023 Jan.
Article in English | MEDLINE | ID: covidwho-2311297
ABSTRACT
The coronavirus disease 2019 (COVID-19) pandemic created an unprecedented challenge for healthcare, and the world continues to struggle in recovering from its aftermath. COVID-19 has been clearly linked to hypercoagulable states and can lead to end-organ ischemia, morbidity, and mortality. Immunosuppressed solid organ transplant recipients represent a highly vulnerable population for the increased risk of complications and mortality. Early venous or arterial thrombosis with acute graft loss after whole pancreas transplantation is well-described, but late thrombosis is rare. We herein report a case of acute, late pancreas graft thrombosis at 13 years post pancreas-after-kidney (PAK) transplantation coinciding with an acute COVID-19 infection in a previously double-vaccinated recipient.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Topics: Vaccines Language: English Journal: Cureus Year: 2023 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Topics: Vaccines Language: English Journal: Cureus Year: 2023 Document Type: Article