Acute encephalomyelitis in a 52-year-old male post messenger ribonucleic acid severe acute respiratory syndrome coronavirus 2 vaccination: a case report.
J Med Case Rep
; 17(1): 202, 2023 May 05.
Article
in English
| MEDLINE | ID: covidwho-2312350
ABSTRACT
BACKGROUND:
Acute disseminated encephalomyelitis is a well-known, but rare, side effect of some vaccines, or symptom following a febrile illness. CASE A 69-year-old, otherwise healthy Hispanic male presented with acute fever, confusion, and later progressive weakness after receiving the first dose of the mRNA-1273 (Moderna) severe acute respiratory syndrome coronavirus 2 vaccine. Considering the progressive deterioration of the patient, despite being on multiple immunosuppressive agents, a brain biopsy was obtained, which revealed nonspecific meningoencephalitis.CONCLUSION:
In this case, we highlight the need for a regulatory framework to assist clinicians and patients with coverage of treatment for acute disseminated encephalomyelitis. The use of intravenous immunoglobulin in conjunction with glucocorticoids seems to be an effective treatment option.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Vaccines
/
Encephalomyelitis, Acute Disseminated
/
Encephalomyelitis
/
COVID-19
Type of study:
Case report
Topics:
Long Covid
/
Vaccines
Limits:
Aged
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
J Med Case Rep
Year:
2023
Document Type:
Article
Affiliation country:
S13256-023-03831-2
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