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Acute encephalomyelitis in a 52-year-old male post messenger ribonucleic acid severe acute respiratory syndrome coronavirus 2 vaccination: a case report.
Alebna, Pamela Lamisi; Shahid, Muhammad Ahmad; Brannan, Timothy; Shen, Ting; Marian, Valentin.
  • Alebna PL; Internal Medicine, Rutgers/Robert Wood Johnson Barnabas Health Jersey City Medical Center, 355 Grand Street, Jersey City, NJ, 07302, USA. pamela.alebna@rwjbh.org.
  • Shahid MA; Internal Medicine, Rutgers/Robert Wood Johnson Barnabas Health Jersey City Medical Center, 355 Grand Street, Jersey City, NJ, 07302, USA.
  • Brannan T; Neurology, Rutgers/Robert Wood, Johnson Barnabas Health Jersey City Medical Center, Jersey City, USA.
  • Shen T; Pathology, Rutgers/Robert Wood Johnson Barnabas Health Jersey City Medical Center, Jersey City, USA.
  • Marian V; Rheumatology, Rutgers/Robert Wood Johnson Barnabas Health Jersey City Medical Center, Jersey City, USA.
J Med Case Rep ; 17(1): 202, 2023 May 05.
Article in English | MEDLINE | ID: covidwho-2312350
ABSTRACT

BACKGROUND:

Acute disseminated encephalomyelitis is a well-known, but rare, side effect of some vaccines, or symptom following a febrile illness. CASE A 69-year-old, otherwise healthy Hispanic male presented with acute fever, confusion, and later progressive weakness after receiving the first dose of the mRNA-1273 (Moderna) severe acute respiratory syndrome coronavirus 2 vaccine. Considering the progressive deterioration of the patient, despite being on multiple immunosuppressive agents, a brain biopsy was obtained, which revealed nonspecific meningoencephalitis.

CONCLUSION:

In this case, we highlight the need for a regulatory framework to assist clinicians and patients with coverage of treatment for acute disseminated encephalomyelitis. The use of intravenous immunoglobulin in conjunction with glucocorticoids seems to be an effective treatment option.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / Encephalomyelitis, Acute Disseminated / Encephalomyelitis / COVID-19 Type of study: Case report Topics: Long Covid / Vaccines Limits: Aged / Humans / Male / Middle aged Language: English Journal: J Med Case Rep Year: 2023 Document Type: Article Affiliation country: S13256-023-03831-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / Encephalomyelitis, Acute Disseminated / Encephalomyelitis / COVID-19 Type of study: Case report Topics: Long Covid / Vaccines Limits: Aged / Humans / Male / Middle aged Language: English Journal: J Med Case Rep Year: 2023 Document Type: Article Affiliation country: S13256-023-03831-2